Panama, Panama City, Santa Ana neighborhood, Fish Market (Mercado de Mariscos). Woman seller. Freshly caught fish and seafood at the fish market in Panama City, Panama, Central America. The Mercado de Mariscos is the city fish market, open for business to local restaurants and the public every day except the 3rd Monday of each month when it is closed completely for thorough cleaning. It's the best place to buy fresh fish in Panama City - everything from tuna to snapper to lobster to octopus - or ceviche to go from one of the many vendors. It's bustling with energy like a true open market and there is a very good casual restaurant upstairs.